L-HPC

L-HPC (Low-Substituted Hydroxypropyl Cellulose) was first approved in 1977 as a disintegrant for pharmaceutical dosage forms in Japan.

 

A recent survey shows that L-HPC is ranked as the first choice of tablet disintegrant by Japanese pharmaceutical companies.

 

The key benefits of L-HPC include:

  • Excellent compatibility with active ingredients
  • Disintegration into smaller particles leading to better dissolution
  • Anti-capping effect for tableting process
  • Suitable for pellet extrusion as well as tableting
  • A variety of grades are available depending on application

 

L-HPC Applications


One of the benefits of L-HPC is to resolve “capping,” which is a typical problem in the tableting process. Several reports have highlighted that capping is caused by a high residual die-wall pressure during the tableting process. L-HPC reduces the residual die-wall force and ejection force during the tableting process. For this application we recommend that you use either LH-11 or NBD-020.


Downloads

» Guide to Applications

» Pharmaceutical Excipients

Requests

» Send your Request by e-mail

e.g. Technical Information,

Material Safety Data Sheet and Samples

need to be requested by e-mail

Contact Information

Phone: 973-837-8001

E-mail: Contact-pharma@setyloseusa.com